| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 3 |
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| Ligand | BDBM50353238 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC Inhibition Assay |
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| IC50 | 1.90±n/a nM |
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| Citation |  Hooker, JM; Wang, C; Schroeder, FA Imaging histone deacetylases with a radiotracer using positron emission tomography US Patent US10188756 Publication Date 1/29/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 3 |
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| Name: | Histone deacetylase 3 |
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| Synonyms: | HD3 | HDAC3 | HDAC3_HUMAN | Histone deacetylase 3 (HDAC3) | Human HDAC3 | RPD3-2 | SMAP45 |
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| Type: | Enzyme |
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| Mol. Mass.: | 48829.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O15379 |
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| Residue: | 428 |
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| Sequence: | MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCR
FHSEDYIDFLQRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNN
KICDIAINWAGGLHHAKKFEASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEA
FYLTDRVMTVSFHKYGNYFFPGTGDMYEVGAESGRYYCLNVPLRDGIDDQSYKHLFQPVI
NQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECVEYVKSFNIPLLVLGGGGYTV
RNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQNSRQYLDQIRQ
TIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN
DKESDVEI
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| BDBM50353238 |
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| n/a |
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| Name | BDBM50353238 |
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| Synonyms: | CHEMBL1830399 | US10188756, Compound CN101 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N4O2 |
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| Mol. Mass. | 330.4246 |
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| SMILES | CCCCc1nc2cc(\C=C\C(=O)NO)ccc2n1CCN(C)C |
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| Structure | 
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