Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(1A) dopamine receptor | ||
| Ligand | BDBM200977 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Binding Assay | ||
| pH | 7.4±n/a | ||
| Ki | 141±0 nM | ||
| Comments | extracted | ||
| Citation |  Gray, DL; Zhang, L; Brodney, MA; Green, ME; Subramanyam, C Substituted 1,7-naphthyridines as dopamine D1 ligands US Patent US9540352 Publication Date 1/10/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(1A) dopamine receptor | |||
| Name: | D(1A) dopamine receptor | ||
| Synonyms: | DA D1 receptor | DOPAMINE D1 | DRD1 | DRD1_HUMAN | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 49303.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21728 | ||
| Residue: | 446 | ||
| Sequence: |
| ||
| BDBM200977 | |||
| n/a | |||
| Name | BDBM200977 | ||
| Synonyms: | 4,6-dimethyl-5-[2-methyl-4-(2,7-naphthyridin- 1-yloxy)phenyl]pyridazin-3(2H)-one | US9540352, example 8 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H18N4O2 | ||
| Mol. Mass. | 358.3932 | ||
| SMILES | Cc1cc(Oc2nccc3ccncc23)ccc1-c1c(C)n[nH]c(=O)c1C |(.67,3.47,;.67,1.93,;-.67,1.15,;-.67,-.38,;-2,-1.15,;-2,-2.69,;-.67,-3.47,;-.67,-5,;-2,-5.78,;-3.33,-5,;-4.67,-5.78,;-6,-5,;-6,-3.47,;-4.67,-2.69,;-3.33,-3.47,;.67,-1.15,;2,-.38,;2,1.15,;3.33,1.93,;4.67,1.15,;4.67,-.38,;6,1.93,;6,3.47,;4.67,4.23,;4.67,5.78,;3.33,3.47,;2,4.23,)| | ||
| Structure | 
| ||