| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucagon-like peptide 1 receptor |
|---|
| Ligand | BDBM615594 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Tag-Lite Binding Assay |
|---|
| Ki | 82.7±n/a nM |
|---|
| Citation |  Liang, B; Yang, Y; Wang, P; Yang, B; Lai, Y; Wu, JJ GLP-1R MODULATING COMPOUNDS US Patent US20230271949 Publication Date 8/31/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glucagon-like peptide 1 receptor |
|---|
| Name: | Glucagon-like peptide 1 receptor |
|---|
| Synonyms: | GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 53035.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43220 |
|---|
| Residue: | 463 |
|---|
| Sequence: | MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL
FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW
RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH
LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN
YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN
SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL
GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW
RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
|
|
|
|---|
| BDBM615594 |
|---|
| n/a |
|---|
| Name | BDBM615594 |
|---|
| Synonyms: | US20230271949, Example 385 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C41H38ClFN6O4 |
|---|
| Mol. Mass. | 733.23 |
|---|
| SMILES | Cc1n[nH]c2c(C)cc(cc12)C(=O)Nc1ccc2n(CC3CCO3)c(CN3CCC(=CC3)c3cccc4O[C@](C)(Oc34)c3ccc(Cl)cc3F)nc2c1 |r,c:32| |
|---|
| Structure | 
|
|---|
Search and Browse
