Reaction Details | |||
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Target | Bromodomain-containing protein 4 [342-460] | ||
Ligand | BDBM363500 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | AlphaScreen Assay | ||
IC50 | <200±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Bromodomain-containing protein 4 [342-460] | |||
Name: | Bromodomain-containing protein 4 [342-460] | ||
Synonyms: | BRD4 | BRD4-BD2 (aa 342-460) | BRD4_HUMAN | Bromodomain containing 4 (aa 342-460) | Bromodomain-containing protein 4 (BRD4)(BD2) | HUNK1 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 13783.81 | ||
Organism: | Homo sapiens (Human) | ||
Description: | a.a. 342-460 (BRD4-BD2) | ||
Residue: | 119 | ||
Sequence: |
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BDBM363500 | |||
n/a | |||
Name | BDBM363500 | ||
Synonyms: | 9-(3,5-Dimethylisoxazol-4-yl)-6-methoxy-3-pyridin-2-yl-2,3-dihydro[1,4]oxazino[2,3,4-hi]indazole | US9850257, Example 7 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H18N4O3 | ||
Mol. Mass. | 362.3819 | ||
SMILES | COc1nn2C(COc3c(ccc1c23)-c1c(C)noc1C)c1ccccn1 |(3.4,12.23,;3.8,10.74,;2.71,9.65,;.04,9.65,;.04,8.11,;-1.29,7.34,;-1.29,5.8,;.04,5.03,;1.38,5.8,;2.71,5.03,;4.04,5.8,;4.04,7.34,;2.71,8.11,;1.38,7.34,;2.71,3.49,;1.47,2.58,;.13,3.35,;1.94,1.12,;3.48,1.12,;3.96,2.58,;5.29,3.35,;-2.62,8.11,;-2.62,9.65,;-3.96,10.42,;-5.29,9.65,;-5.29,8.11,;-3.96,7.34,)| | ||
Structure | ![]() |