| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin K |
|---|
| Ligand | BDBM19768 |
|---|
| Substrate/Competitor | BDBM20130 |
|---|
| Meas. Tech. | Papain Inhibition Assay |
|---|
| Ki | 35±n/a nM |
|---|
| Citation |  Löser, R; Schilling, K; Dimmig, E; Gütschow, M Interaction of papain-like cysteine proteases with dipeptide-derived nitriles. J Med Chem48:7688-707 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Cathepsin K |
|---|
| Name: | Cathepsin K |
|---|
| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 36975.68 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P43235 |
|---|
| Residue: | 329 |
|---|
| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
|
|
|
|---|
| BDBM19768 |
|---|
| BDBM20130 |
|---|
| Name | BDBM19768 |
|---|
| Synonyms: | Cbz-Leu-NH-CH2-CN | JMC487688 Compound 8 | benzyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-3-methylbutyl]carbamate | dipeptidyl nitrile, 1 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H21N3O3 |
|---|
| Mol. Mass. | 303.3562 |
|---|
| SMILES | CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCC#N |r| |
|---|
| Structure | 
|
|---|
Search and Browse
