| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM364558 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Mu-Opioid Receptor Binding Assay |
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| Ki | 136±35.7 nM |
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| Citation |  Youngman, M Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans US Patent US9862726 Publication Date 1/9/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM364558 |
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| n/a |
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| Name | BDBM364558 |
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| Synonyms: | N-((4bR,6S,8aS,9R)-11- (cyclopropylmethyl)- 3-methoxy-5,6,7,8,9,10-hexahydro-9,4b- (epiminoethano)-8a,6- (epoxymethano)phenanthren-6-yl)-3,3,3- trifluoropropanamide | US9862726, Compound 23 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31F3N2O3 |
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| Mol. Mass. | 464.5204 |
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| SMILES | COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC5(CC[C@@]34OC5)NC(=O)CC(F)(F)F)c2c1 |r,TLB:9:8:20:31.5.6| |
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| Structure | 
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