| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 4 |
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| Ligand | BDBM366046 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Activity Assay |
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| IC50 | 630±n/a nM |
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| Citation |  Sakuma, S; Kobayashi, K; Ushioda, M; Saito, D; Imai, T; Inoue, K P2X4 receptor antagonist US Patent US9873683 Publication Date 1/23/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 4 |
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| Name: | P2X purinoceptor 4 |
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| Synonyms: | ATP receptor | P2RX4 | P2RX4_HUMAN | P2X4 | Purinergic receptor | Purinergic, P2X4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43374.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purinergic, P2X4 0 HUMAN::Q99571 |
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| Residue: | 388 |
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| Sequence: | MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
MKKRLYYREKKYKYVEDYEQGLASELDQ
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| BDBM366046 |
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| n/a |
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| Name | BDBM366046 |
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| Synonyms: | US9873683, Example 40 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H22N6O |
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| Mol. Mass. | 458.5139 |
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| SMILES | O=C1CN=C(c2ccc(cc2)-n2nnnc2CCc2ccccc2)c2ccc3ccccc3c2N1 |t:3| |
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| Structure | 
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