| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Vascular endothelial growth factor A |
|---|
| Ligand | BDBM372997 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ELISA Assay |
|---|
| EC50 | 1580±n/a nM |
|---|
| Citation |  Dixon, DD; Grina, J; Josey, JA; Rizzi, JP; Schlachter, ST; Wallace, EM; Wang, B; Wehn, P; Xu, R; Yang, H Aryl ethers and uses thereof US Patent US9908845 Publication Date 3/6/2018 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Vascular endothelial growth factor A |
|---|
| Name: | Vascular endothelial growth factor A |
|---|
| Synonyms: | VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 27063.81 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P15692 |
|---|
| Residue: | 395 |
|---|
| Sequence: | MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLG
CSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWT
GEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASET
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQ
DPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
|
|
|
|---|
| BDBM372997 |
|---|
| n/a |
|---|
| Name | BDBM372997 |
|---|
| Synonyms: | US10597366, Compound 98 | US9896418, Compound 98 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H5BrClF4NO3S |
|---|
| Mol. Mass. | 458.61 |
|---|
| SMILES | Fc1cc(Cl)cc(Oc2ccc(c(C#N)c2Br)S(=O)(=O)C(F)(F)F)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
