Reaction Details |
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Target | Vascular endothelial growth factor A |
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Ligand | BDBM373032 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ELISA Assay |
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EC50 | 81.0±n/a nM |
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Citation | Dixon, DD; Grina, J; Josey, JA; Rizzi, JP; Schlachter, ST; Wallace, EM; Wang, B; Wehn, P; Xu, R; Yang, H Aryl ethers and uses thereof US Patent US9908845 Publication Date 3/6/2018 |
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More Info.: | Get all data from this article, Assay Method |
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Vascular endothelial growth factor A |
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Name: | Vascular endothelial growth factor A |
Synonyms: | VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor |
Type: | Protein |
Mol. Mass.: | 27063.81 |
Organism: | Homo sapiens (Human) |
Description: | P15692 |
Residue: | 395 |
Sequence: | MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLG
CSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWT
GEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASET
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQ
DPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
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BDBM373032 |
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n/a |
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Name | BDBM373032 |
Synonyms: | US10597366, Compound 245 | US9896418, Compound 240 | US9896418, Compound 245 |
Type | Small organic molecule |
Emp. Form. | C18H12F3N3O3S |
Mol. Mass. | 407.366 |
SMILES | CS(=O)(=NC#N)c1ccc(Oc2cc(F)cc(c2)C#N)c2CC(F)(F)[C@@H](O)c12 |r| |
Structure |
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