| Reaction Details |
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 | Report a problem with these data |
| Target | Low molecular weight protein-tyrosine phosphatase A |
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| Ligand | BDBM26104 |
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| Substrate/Competitor | BDBM13466 |
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| Meas. Tech. | Determination of Inhibitor Ki |
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| pH | 7.4±n/a |
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| Temperature | 295.15±n/a K |
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| Ki | >50000±n/a nM |
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| Citation |  Soellner, MB; Rawls, KA; Grundner, C; Alber, T; Ellman, JA Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB. J Am Chem Soc129:9613-5 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Low molecular weight protein-tyrosine phosphatase A |
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| Name: | Low molecular weight protein-tyrosine phosphatase A |
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| Synonyms: | PTPA_MYCTU | PTPase | Probable low molecular weight protein-tyrosine-phosphatase | Protein Tyrosine Phosphatase PTPA | mptpA | ptpA |
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| Type: | Hydrolase |
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| Mol. Mass.: | 17891.84 |
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| Organism: | Mycobacterium tuberculosis |
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| Description: | n/a |
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| Residue: | 163 |
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| Sequence: | MSDPLHVTFVCTGNICRSPMAEKMFAQQLRHRGLGDAVRVTSAGTGNWHVGSCADERAAG
VLRAHGYPTDHRAAQVGTEHLAADLLVALDRNHARLLRQLGVEAARVRMLRSFDPRSGTH
ALDVEDPYYGDHSDFEEVFAVIESALPGLHDWVDERLARNGPS
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| BDBM26104 |
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| BDBM13466 |
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| Name | BDBM26104 |
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| Synonyms: | 5-{2-cyclohexyl-4-[4-fluoro-3-(trifluoromethyl)phenyl]phenyl}-1,2-oxazole-3-carboxylic acid | Isoxazole carboxylic acid, 19 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19F4NO3 |
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| Mol. Mass. | 433.3955 |
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| SMILES | OC(=O)c1cc(on1)-c1ccc(cc1C1CCCCC1)-c1ccc(F)c(c1)C(F)(F)F |
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| Structure | 
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