| Reaction Details |
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 | Report a problem with these data |
| Target | P2X purinoceptor 4 |
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| Ligand | BDBM393619 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Antagonist Activity Assay |
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| IC50 | 1800±0.0 nM |
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| Citation |  Ushioda, M; Kobayashi, K; Saito, D; Sakuma, S; Imai, T; Inoue, K P2X4 receptor antagonist US Patent US9969700 Publication Date 5/15/2018 |
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| More Info.: | Get all data from this article, Assay Method |
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| P2X purinoceptor 4 |
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| Name: | P2X purinoceptor 4 |
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| Synonyms: | ATP receptor | P2RX4 | P2RX4_HUMAN | P2X4 | Purinergic receptor | Purinergic, P2X4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43374.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Purinergic, P2X4 0 HUMAN::Q99571 |
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| Residue: | 388 |
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| Sequence: | MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
MKKRLYYREKKYKYVEDYEQGLASELDQ
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| BDBM393619 |
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| n/a |
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| Name | BDBM393619 |
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| Synonyms: | 5-[4-(2-Iodobenzoyl)aminophenyl]-1,2,3,4,8,9,10,11-octahydronaphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | US09969700, 106 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30IN3O3 |
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| Mol. Mass. | 571.4499 |
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| SMILES | Ic1ccccc1CC(=O)Nc1ccc(cc1)N1C2CCC3CCCCC3C2NC(=O)CC1=O |
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| Structure | 
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