| Reaction Details |
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 | Report a problem with these data |
| Target | Tubulin--tyrosine ligase |
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| Ligand | BDBM18129 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | [3H]-Tyr Incorporation Assay |
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| pH | 6.8±0 |
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| Temperature | 310.15±0 K |
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| Ki | 25000±0.0 nM |
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| Citation |  Banerjee, A; Panosian, TD; Mukherjee, K; Ravindra, R; Gal, S; Sackett, DL; Bane, S Site-specific orthogonal labeling of the carboxy terminus of alpha-tubulin. ACS Chem Biol5:777-85 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tubulin--tyrosine ligase |
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| Name: | Tubulin--tyrosine ligase |
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| Synonyms: | TTL | TTL_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 43213.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_519880 |
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| Residue: | 377 |
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| Sequence: | MYTFVVRDENSSVYAEVSRLLLATGHWKRLRRDNPRFNLMLGERNRLPFGRLGHEPGLVQ
LVNYYRGADKLCRKASLVKLIKTSPELAESCTWFPESYVIYPTNLKTPVAPAQNGIQPPI
SNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDFIDNQGQVH
VIQKYLEHPLLLEPGHRKFDIRSWVLVDHQYNIYLYREGVLRTASEPYHVDNFQDKTCHL
TNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCLLSVEP
AISTKHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPACAQKLYAELCQGIVDIAISSVFP
PPDVEQPQTQPAAFIKL
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| BDBM18129 |
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| n/a |
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| Name | BDBM18129 |
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| Synonyms: | (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid | L-[U-14C]Tyr | Tyrosine | US11021454, Compound L-tyr |
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| Type | Amino Acid |
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| Emp. Form. | C9H11NO3 |
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| Mol. Mass. | 181.1885 |
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| SMILES | N[C@@H](Cc1ccc(O)cc1)C(O)=O |
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| Structure | 
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