Reaction Details | |||
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Target | Tyrosine-protein kinase BTK | ||
Ligand | BDBM264143 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Human Recombinant Btk Enzyme Assay | ||
pH | 7.4±n/a | ||
Temperature | 298.15±n/a K | ||
IC50 | 2.30±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein kinase BTK | |||
Name: | Tyrosine-protein kinase BTK | ||
Synonyms: | AGMX1 | ATK | Agammaglobulinaemia tyrosine kinase | Agammaglobulinemia tyrosine kinase | B cell progenitor kinase | B-cell progenitor kinase | BPK | BTK | BTK_HUMAN | Bruton tyrosine kinase | Tyrosine Kinase BTK | Tyrosine-protein kinase (BTK) | Tyrosine-protein kinase BTK (BTK) | ||
Type: | Enzyme | ||
Mol. Mass.: | 76289.95 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q06187 | ||
Residue: | 659 | ||
Sequence: |
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BDBM264143 | |||
n/a | |||
Name | BDBM264143 | ||
Synonyms: | 4-(3-(5-Fluoro-1,3-dioxo-1H-pyrido[1,2-c]pyrimidin-2(3H)-yl)-2-methylphenyl)-7-(methoxymethyl)-9H-carbazole-1-carboxamide (Mixture of Four diastereomers) | US9714234, 18 | ||
Type | Small organic molecule | ||
Emp. Form. | C30H23FN4O4 | ||
Mol. Mass. | 522.5264 | ||
SMILES | Cc1c(cccc1-n1c(=O)cc2c(F)cccn2c1=O)-c1ccc(C(N)=O)c2[nH]c3cc(CCO)ccc3c12 |(2.96,.56,;2.19,-.77,;.85,,;-.48,-.77,;-.48,-2.31,;.85,-3.08,;2.19,-2.31,;3.52,-3.08,;3.52,-4.62,;2.19,-5.39,;4.86,-5.39,;6.19,-4.62,;7.52,-5.39,;7.52,-6.93,;8.86,-4.62,;8.86,-3.08,;7.52,-2.31,;6.19,-3.08,;4.86,-2.31,;4.86,-.77,;.85,1.54,;2.19,2.31,;2.19,3.85,;.85,4.62,;.85,6.16,;2.19,6.93,;-.48,6.93,;-.48,3.85,;-1.94,4.33,;-2.85,3.08,;-4.38,2.92,;-5.01,1.51,;-6.54,1.35,;-7.44,2.6,;-8.98,2.44,;-4.1,.27,;-2.57,.43,;-1.94,1.83,;-.48,2.31,)| | ||
Structure | ![]() |