| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 10 |
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| Ligand | BDBM42742 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) |
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| IC50 | 7928±n/a nM |
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| Citation |  PubChem, PC Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) PubChem Bioassay(2008)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitogen-activated protein kinase 10 |
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| Name: | Mitogen-activated protein kinase 10 |
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| Synonyms: | JNK3 | JNK3A | MAP kinase p49 3F12 | MAPK10 | MK10_HUMAN | Mitogen-Activated Protein Kinase 10 (JNK3) | Mitogen-activated protein kinase 10 (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) | Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 | PRKM10 | SAPK1B | Stress-activated protein kinase JNK3 | c-Jun N-terminal kinase 3 (JNK3) |
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| Type: | Enzyme |
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| Mol. Mass.: | 52586.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 464 |
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| Sequence: | MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
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| BDBM42742 |
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| n/a |
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| Name | BDBM42742 |
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| Synonyms: | MLS000092689 | N-(4-cyanophenyl)-3-(4-fluorophenyl)-2-isoxazoline-5-carboxamide | N-(4-cyanophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1,2-oxazole-5-carboxamide | N-(4-cyanophenyl)-3-(4-fluorophenyl)-4,5-dihydroisoxazole-5-carboxamide | SMR000028380 | cid_3243409 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12FN3O2 |
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| Mol. Mass. | 309.2945 |
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| SMILES | Fc1ccc(cc1)C1=NOC(C1)C(=O)Nc1ccc(cc1)C#N |t:8| |
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| Structure | 
|
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