| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 10 |
|---|
| Ligand | BDBM42830 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) |
|---|
| IC50 | 809±n/a nM |
|---|
| Citation |  PubChem, PC Dose response biochemical screening assay for inhibitors of c-Jun N-Terminal Kinase 3 (JNK3) PubChem Bioassay(2008)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mitogen-activated protein kinase 10 |
|---|
| Name: | Mitogen-activated protein kinase 10 |
|---|
| Synonyms: | JNK3 | JNK3A | MAP kinase p49 3F12 | MAPK10 | MK10_HUMAN | Mitogen-Activated Protein Kinase 10 (JNK3) | Mitogen-activated protein kinase 10 (Stress-activated protein kinase JNK3) (c-Jun N-terminal kinase 3) (MAP kinase p49 3F12) | Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1 | PRKM10 | SAPK1B | Stress-activated protein kinase JNK3 | c-Jun N-terminal kinase 3 (JNK3) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 52586.89 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 464 |
|---|
| Sequence: | MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
|
|
|
|---|
| BDBM42830 |
|---|
| n/a |
|---|
| Name | BDBM42830 |
|---|
| Synonyms: | 6-[(2-methyl-1,3-thiazol-4-yl)methylsulfanyl]-5-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-one | 6-[(2-methyl-4-thiazolyl)methylthio]-5-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-one | 6-[(2-methylthiazol-4-yl)methylthio]-5-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-one | 6-{[(2-methyl-1,3-thiazol-4-yl)methyl]thio}-5-phenyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | MLS000049487 | SMR000075496 | cid_1288597 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H13N5OS2 |
|---|
| Mol. Mass. | 355.437 |
|---|
| SMILES | Cc1nc(CSc2nc3n[nH]cc3c(=O)n2-c2ccccc2)cs1 |
|---|
| Structure | 
|
|---|
Search and Browse
