| Reaction Details |
|---|
 | Report a problem with these data |
| Target | SRSF protein kinase 1 |
|---|
| Ligand | BDBM101659 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Kinase Assay |
|---|
| Temperature | 303.15±n/a K |
|---|
| IC50 | 38±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Bates, D; Morris, J Piperazine derivatives for treating disorders US Patent US9695160 Publication Date 7/4/2017 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| SRSF protein kinase 1 |
|---|
| Name: | SRSF protein kinase 1 |
|---|
| Synonyms: | SRPK1 | SRPK1_HUMAN | SRSF protein kinase 1 (SRPK1) | Serine/arginine-protein kinase 1 (SRPK1) | Serine/threonine-protein kinase SRPK1 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 74318.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q96SB4 |
|---|
| Residue: | 655 |
|---|
| Sequence: | MERKVLALQARKKRTKAKKDKAQRKSETQHRGSAPHSESDLPEQEEEILGSDDDEQEDPN
DYCKGGYHLVKIGDLFNGRYHVIRKLGWGHFSTVWLSWDIQGKKFVAMKVVKSAEHYTET
ALDEIRLLKSVRNSDPNDPNREMVVQLLDDFKISGVNGTHICMVFEVLGHHLLKWIIKSN
YQGLPLPCVKKIIQQVLQGLDYLHTKCRIIHTDIKPENILLSVNEQYIRRLAAEATEWQR
SGAPPPSGSAVSTAPQPKPADKMSKNKKKKLKKKQKRQAELLEKRMQEIEEMEKESGPGQ
KRPNKQEESESPVERPLKENPPNKMTQEKLEESSTIGQDQTLMERDTEGGAAEINCNGVI
EVINYTQNSNNETLRHKEDLHNANDCDVQNLNQESSFLSSQNGDSSTSQETDSCTPITSE
VSDTMVCQSSSTVGQSFSEQHISQLQESIRAEIPCEDEQEQEHNGPLDNKGKSTAGNFLV
NPLEPKNAEKLKVKIADLGNACWVHKHFTEDIQTRQYRSLEVLIGSGYNTPADIWSTACM
AFELATGDYLFEPHSGEEYTRDEDHIALIIELLGKVPRKLIVAGKYSKEFFTKKGDLKHI
TKLKPWGLFEVLVEKYEWSQEEAAGFTDFLLPMLELIPEKRATAAECLRHPWLNS
|
|
|
|---|
| BDBM101659 |
|---|
| n/a |
|---|
| Name | BDBM101659 |
|---|
| Synonyms: | US9695160, 16 | US9796707, Compound 16 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H23F3N4O2 |
|---|
| Mol. Mass. | 444.4495 |
|---|
| SMILES | Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccccn2)CC1)C(F)(F)F |
|---|
| Structure | 
|
|---|
Search and Browse
