| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
|---|
| Ligand | BDBM50132292 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
|---|
| IC50 | >118462±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| RecBCD enzyme subunit RecD |
|---|
| Name: | RecBCD enzyme subunit RecD |
|---|
| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 66906.68 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130723 |
|---|
| Residue: | 608 |
|---|
| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
|
|
|
|---|
| BDBM50132292 |
|---|
| n/a |
|---|
| Name | BDBM50132292 |
|---|
| Synonyms: | 5-Ethyl-1-((2R,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione | 5-ethyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione | 5-ethyl-2'-deoxyuridine | CHEMBL318153 | Edoxudine | cid_1814 | cid_66377 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H16N2O5 |
|---|
| Mol. Mass. | 256.2551 |
|---|
| SMILES | CCc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
