Ki Summary

Reaction Details

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Target

RecBCD enzyme subunit RecD

Ligand

BDBM60214

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD

IC50

44242±n/a nM

Citation

PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

RecBCD enzyme subunit RecD

Name:

RecBCD enzyme subunit RecD

Synonyms:

RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD

Type:

Enzyme Catalytic Domain

Mol. Mass.:

66906.68

Organism:

Escherichia coli str. K-12 substr. MG1655

Description:

gi_16130723

Residue:

608

Sequence:

MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE

BDBM60214

n/a

Name

BDBM60214

Synonyms:

4-chloranyl-N-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide | 4-chloro-N-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide | MLS000057767 | SMR000061562 | cid_805087

Type

Small organic molecule

Emp. Form.

C15H10ClN3O2

Mol. Mass.

299.712

SMILES

Clc1ccc(cc1)C(=O)Nc1nnc(o1)-c1ccccc1

Structure