| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
|---|
| Ligand | BDBM46756 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
|---|
| IC50 | 68155±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| RecBCD enzyme subunit RecD |
|---|
| Name: | RecBCD enzyme subunit RecD |
|---|
| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 66906.68 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130723 |
|---|
| Residue: | 608 |
|---|
| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
|
|
|
|---|
| BDBM46756 |
|---|
| n/a |
|---|
| Name | BDBM46756 |
|---|
| Synonyms: | MLS000103340 | N-(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)-3-(trifluoromethyl)benzamide | N-[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]-3-(trifluoromethyl)benzamide | SMR000018744 | cid_2104451 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H8F3N3O2S |
|---|
| Mol. Mass. | 339.292 |
|---|
| SMILES | FC(F)(F)c1cccc(c1)C(=O)Nc1nnc(o1)-c1cccs1 |
|---|
| Structure | 
|
|---|
Search and Browse
