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TargetRecBCD enzyme subunit RecD
LigandBDBM40695
Substrate/Competitorn/a
Meas. Tech.Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
IC50 28433±n/a nM
Citation PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
RecBCD enzyme subunit RecD
Name:RecBCD enzyme subunit RecD
Synonyms:RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:Enzyme Catalytic Domain
Mol. Mass.:66906.68
Organism:Escherichia coli str. K-12 substr. MG1655
Description:gi_16130723
Residue:608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM40695
n/a
NameBDBM40695
Synonyms:10-(4-bromophenyl)-9-(4-methylphenyl)-7,8-dihydroimidazo[1,2-a][1,10]phenanthrolin-12-ium;bromide | 10-(4-bromophenyl)-9-(p-tolyl)-7,8-dihydroimidazo[1,2-a][1,10]phenanthrolin-12-ium;bromide | MLS000565339 | SMR000152588 | cid_9551998
TypeSmall organic molecule
Emp. Form.C27H21BrN3
Mol. Mass.467.379
SMILESCc1ccc(cc1)-n1c(c[n+]-2c1CCc1ccc3cccnc3c-21)-c1ccc(Br)cc1
Structure
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