| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
|---|
| Ligand | BDBM75744 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
|---|
| IC50 | 72809±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| RecBCD enzyme subunit RecD |
|---|
| Name: | RecBCD enzyme subunit RecD |
|---|
| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 66906.68 |
|---|
| Organism: | Escherichia coli str. K-12 substr. MG1655 |
|---|
| Description: | gi_16130723 |
|---|
| Residue: | 608 |
|---|
| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
|
|
|
|---|
| BDBM75744 |
|---|
| n/a |
|---|
| Name | BDBM75744 |
|---|
| Synonyms: | (2E)-3-ethyl-2-[(1-ethyl-2-quinolin-1-iumyl)methylidene]-6-methyl-1,3-benzothiazole;iodide | (2E)-3-ethyl-2-[(1-ethylquinolin-1-ium-2-yl)methylene]-6-methyl-1,3-benzothiazole;iodide | (2E)-3-ethyl-2-[(1-ethylquinolin-1-ium-2-yl)methylidene]-6-methyl-1,3-benzothiazole;iodide | MLS000688479 | SMR000284410 | cid_16187754 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H23N2S |
|---|
| Mol. Mass. | 347.496 |
|---|
| SMILES | CCN1\C(Sc2cc(C)ccc12)=C/c1ccc2ccccc2[n+]1CC |
|---|
| Structure | 
|
|---|
Search and Browse
