| Reaction Details |
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 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
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| Ligand | BDBM77552 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
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| IC50 | 27479±n/a nM |
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| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RecBCD enzyme subunit RecD |
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| Name: | RecBCD enzyme subunit RecD |
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| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66906.68 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130723 |
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| Residue: | 608 |
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| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
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| BDBM77552 |
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| n/a |
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| Name | BDBM77552 |
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| Synonyms: | 5-[2-(2-pyridinylmethylidene)hydrazinyl]-2H-1,2,4-triazin-3-one | 5-[2-(pyridin-2-ylmethylidene)hydrazinyl]-2H-1,2,4-triazin-3-one | 5-[N'-(2-pyridylmethylene)hydrazino]-2H-1,2,4-triazin-3-one | MLS000685728 | SMR000312692 | cid_4603494 | pyridine-2-carbaldehyde (3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone |
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| Type | Small organic molecule |
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| Emp. Form. | C9H8N6O |
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| Mol. Mass. | 216.1994 |
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| SMILES | O=c1nncc(N=NCc2ccccn2)[nH]1 |w:6.5| |
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| Structure | 
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