| Reaction Details |
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 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
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| Ligand | BDBM64703 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
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| IC50 | 102019±n/a nM |
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| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RecBCD enzyme subunit RecD |
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| Name: | RecBCD enzyme subunit RecD |
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| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66906.68 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130723 |
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| Residue: | 608 |
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| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
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| BDBM64703 |
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| n/a |
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| Name | BDBM64703 |
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| Synonyms: | 7-[(2-chlorophenyl)-(1-pyrrolidinyl)methyl]-8-quinolinol | 7-[(2-chlorophenyl)-pyrrolidin-1-yl-methyl]quinolin-8-ol | 7-[(2-chlorophenyl)-pyrrolidin-1-ylmethyl]quinolin-8-ol | 7-[(2-chlorophenyl)-pyrrolidino-methyl]quinolin-8-ol | MLS000761483 | SMR000371583 | cid_5187118 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19ClN2O |
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| Mol. Mass. | 338.831 |
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| SMILES | Oc1c(ccc2cccnc12)C(N1CCCC1)c1ccccc1Cl |
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| Structure | 
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