| Reaction Details |
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 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
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| Ligand | BDBM73790 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
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| IC50 | >118481±n/a nM |
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| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RecBCD enzyme subunit RecD |
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| Name: | RecBCD enzyme subunit RecD |
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| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66906.68 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130723 |
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| Residue: | 608 |
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| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
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| BDBM73790 |
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| n/a |
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| Name | BDBM73790 |
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| Synonyms: | (4-Oxo-2-{[1-pyridin-2-yl-meth-(E)-ylidene]-hydrazono}-thiazolidin-5-yl)-acetic acid | 2-[4-keto-2-[N'-(2-pyridylmethylene)hydrazino]-2-thiazolin-5-yl]acetic acid | 2-[4-oxidanylidene-2-[2-(pyridin-2-ylmethylidene)hydrazinyl]-1,3-thiazol-5-yl]ethanoic acid | 2-[4-oxo-2-[2-(2-pyridinylmethylidene)hydrazinyl]-5-thiazolyl]acetic acid | 2-[4-oxo-2-[2-(pyridin-2-ylmethylidene)hydrazinyl]-1,3-thiazol-5-yl]acetic acid | MLS001044506 | SMR000415001 | cid_3832830 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H10N4O3S |
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| Mol. Mass. | 278.287 |
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| SMILES | OC(=O)Cc1sc(N=NCc2ccccn2)nc1O |w:7.6| |
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| Structure | 
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