| Reaction Details |
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 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
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| Ligand | BDBM77570 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
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| IC50 | 77245±n/a nM |
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| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RecBCD enzyme subunit RecD |
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| Name: | RecBCD enzyme subunit RecD |
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| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66906.68 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130723 |
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| Residue: | 608 |
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| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
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| BDBM77570 |
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| n/a |
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| Name | BDBM77570 |
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| Synonyms: | 3-[(5-nitro-1,3-thiazol-2-yl)sulfanyl]-4-prop-2-enyl-1H-1,2,4-triazol-5-one | 3-[(5-nitro-2-thiazolyl)thio]-4-prop-2-enyl-1H-1,2,4-triazol-5-one | 4-allyl-3-[(5-nitrothiazol-2-yl)thio]-1H-1,2,4-triazol-5-one | 4-allyl-5-[(5-nitro-1,3-thiazol-2-yl)thio]-4H-1,2,4-triazol-3-ol | MLS000850992 | SMR000457009 | cid_2743870 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H7N5O3S2 |
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| Mol. Mass. | 285.303 |
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| SMILES | [O-][N+](=O)c1cnc(Sc2n[nH]c(=O)n2CC=C)s1 |
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| Structure | 
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