BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetRecBCD enzyme subunit RecD
LigandBDBM60273
Substrate/Competitorn/a
Meas. Tech.Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD
IC50>118488±n/a nM
Citation PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
RecBCD enzyme subunit RecD
Name:RecBCD enzyme subunit RecD
Synonyms:RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD
Type:Enzyme Catalytic Domain
Mol. Mass.:66906.68
Organism:Escherichia coli str. K-12 substr. MG1655
Description:gi_16130723
Residue:608
Sequence:
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM60273
n/a
NameBDBM60273
Synonyms:MLS000861866 | N-phenyl-2-[(2-pyridin-2-yl-2,3-dihydro-1,3,4-thiadiazol-5-yl)sulfanyl]acetamide | N-phenyl-2-[(2-pyridin-2-yl-2,3-dihydro-1,3,4-thiadiazol-5-yl)sulfanyl]ethanamide | N-phenyl-2-[[2-(2-pyridinyl)-2,3-dihydro-1,3,4-thiadiazol-5-yl]thio]acetamide | N-phenyl-2-[[2-(2-pyridyl)-2,3-dihydro-1,3,4-thiadiazol-5-yl]thio]acetamide | N1-phenyl-2-{[5-(2-pyridyl)-4,5-dihydro-1,3,4-thiadiazol-2-yl]thio}acetamide | SMR000460650 | cid_2746659
TypeSmall organic molecule
Emp. Form.C15H14N4OS2
Mol. Mass.330.428
SMILESO=C(CSC1=NNC(S1)c1ccccn1)Nc1ccccc1 |t:4|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: