| Reaction Details |
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 | Report a problem with these data |
| Target | RecBCD enzyme subunit RecD |
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| Ligand | BDBM65618 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD |
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| IC50 | >118482±n/a nM |
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| Citation |  PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| RecBCD enzyme subunit RecD |
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| Name: | RecBCD enzyme subunit RecD |
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| Synonyms: | RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66906.68 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130723 |
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| Residue: | 608 |
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| Sequence: | MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE
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| BDBM65618 |
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| n/a |
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| Name | BDBM65618 |
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| Synonyms: | (6E)-2-methoxy-6-[[(5-nitro-2-pyridinyl)hydrazo]methylidene]-1-cyclohexa-2,4-dienone | (6E)-2-methoxy-6-[[2-(5-nitropyridin-2-yl)hydrazinyl]methylidene]cyclohexa-2,4-dien-1-one | (6E)-2-methoxy-6-[[N'-(5-nitro-2-pyridyl)hydrazino]methylene]cyclohexa-2,4-dien-1-one | MLS001173442 | SMR000538788 | cid_5344602 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12N4O4 |
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| Mol. Mass. | 288.2588 |
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| SMILES | COc1ccc[c-](C[NH+]=Nc2ccc(cn2)[N+]([O-])=O)c1=O |w:8.7| |
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| Structure | 
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