Ki Summary

Reaction Details

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Target

RecBCD enzyme subunit RecD

Ligand

BDBM77595

Substrate/Competitor

n/a

Meas. Tech.

Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD

IC50

>118463±n/a nM

Citation

PubChem, PC Counterscreen for AddAB inhibitors: absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

RecBCD enzyme subunit RecD

Name:

RecBCD enzyme subunit RecD

Synonyms:

RECD_ECOLI | exonuclease V (RecBCD complex), alpha chain | hopE | recD

Type:

Enzyme Catalytic Domain

Mol. Mass.:

66906.68

Organism:

Escherichia coli str. K-12 substr. MG1655

Description:

gi_16130723

Residue:

608

Sequence:

MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLEN
NEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVA
RFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAVALTRRISVISGGPGTGKTTT
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQ
LASVEAGAVLGDICAYANAGFTAERARQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYR
FGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQSGEDYIAMLEEALAGYGRYLD
LLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHK
SQGSEFDHAALILPSQRTPVVTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGL
AALFSSRE

BDBM77595

n/a

Name

BDBM77595

Synonyms:

5-nitro-N-(1-propyl-2-benzimidazolyl)-2-furancarboxamide | 5-nitro-N-(1-propylbenzimidazol-2-yl)-2-furamide | 5-nitro-N-(1-propylbenzimidazol-2-yl)furan-2-carboxamide | MLS001138602 | SMR000715180 | cid_24980351

Type

Small organic molecule

Emp. Form.

C15H14N4O4

Mol. Mass.

314.2961

SMILES

CCCn1c(NC(=O)c2ccc(o2)[N+]([O-])=O)nc2ccccc12

Structure