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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase JAK2 | ||
| Ligand | BDBM270879 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | JAK Enzyme Assay | ||
| IC50 | 3600±n/a nM | ||
| Citation |  Gauvry, N; Tahtaoui, C; Furet, P; Ducray, P Compounds US Patent US10059709 Publication Date 8/28/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase JAK2 | |||
| Name: | Tyrosine-protein kinase JAK2 | ||
| Synonyms: | JAK-2 | JAK2 | JAK2_HUMAN | Janus kinase 2 | Janus kinase 2 (JAK2) | Janus kinase 2 (a protein tyrosine kinase) | ||
| Type: | Protein | ||
| Mol. Mass.: | 130684.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60674 | ||
| Residue: | 1132 | ||
| Sequence: |
| ||
| BDBM270879 | |||
| n/a | |||
| Name | BDBM270879 | ||
| Synonyms: | US10059709, 25 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H20N4O5S | ||
| Mol. Mass. | 368.408 | ||
| SMILES | CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)Oc1c(cnc2[nH]ccc12)[N+]([O-])=O |r,wU:6.5,wD:9.12,(6.67,2.8,;5.33,2.03,;4,2.8,;4.77,4.13,;3.23,1.46,;2.67,3.57,;1.33,2.8,;1.33,1.26,;,.49,;-1.33,1.26,;-1.33,2.8,;,3.57,;-2.67,.49,;-2.67,-1.05,;-4,-1.82,;-4,-3.36,;-2.67,-4.13,;-1.33,-3.36,;.13,-3.84,;1.04,-2.59,;.13,-1.35,;-1.33,-1.82,;-5.33,-1.05,;-5.33,.49,;-6.67,-1.82,)| | ||
| Structure | 
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