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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Alpha-1A adrenergic receptor | ||
| Ligand | BDBM50008735 | ||
| Substrate/Competitor | n/a | ||
| Ki | 56±n/a nM | ||
| Comments | PDSP_626 | ||
| Citation |  Richelson, E; Nelson, A Antagonism by neuroleptics of neurotransmitter receptors of normal human brain in vitro. Eur J Pharmacol103:197-204 (1984) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| Alpha-1A adrenergic receptor | |||
| Name: | Alpha-1A adrenergic receptor | ||
| Synonyms: | ADA1A_HUMAN | ADRA1A | ADRA1C | Adrenergic alpha1A | Alpha 1A-adrenoceptor | Alpha 1A-adrenoreceptor | Alpha adrenergic receptor 1a | Alpha-1C adrenergic receptor | Alpha-adrenergic receptor 1c | Cerebral cortex alpha adrenergic receptor | adrenergic Alpha1 | adrenergic Alpha1C | ||
| Type: | Cell-surface receptors | ||
| Mol. Mass.: | 51511.67 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P35348 | ||
| Residue: | 466 | ||
| Sequence: |
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| BDBM50008735 | |||
| n/a | |||
| Name | BDBM50008735 | ||
| Synonyms: | (+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol | (+)-butaclamol | (+/-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol | (S)-(-)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol | 3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol | 3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol ((+)-butaclamol) | 3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[4,5]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol((+)-butaclamol) | 3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,14-octahydro-1H-benzo[6,7]cyclohepta[de]pyrido[2,1-a]isoquinolin-3-ol(Butaclamol) | BUTACLAMOL | BUTACLAMOL, (-) | BUTACLAMOL,(+) | BUTACLAMOL,d- | CHEMBL8514 | d-Butaclamol | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H31NO | ||
| Mol. Mass. | 361.5197 | ||
| SMILES | CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 | ||
| Structure | 
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