| Reaction Details |
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 | Report a problem with these data |
| Target | Substance-K receptor |
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| Ligand | BDBM82262 |
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| Substrate/Competitor | n/a |
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| Ki | 2.2±n/a nM |
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| Comments | PDSP_2000 |
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| Citation |  Aharony, D; Buckner, CK; Ellis, JL; Ghanekar, SV; Graham, A; Kays, JS; Little, J; Meeker, S; Miller, SC; Undem, BJ Pharmacological characterization of a new class of nonpeptide neurokinin A antagonists that demonstrate species selectivity. J Pharmacol Exp Ther274:1216-21 (1995) [PubMed] |
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| More Info.: | Get all data from this article |
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| Substance-K receptor |
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| Name: | Substance-K receptor |
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| Synonyms: | NK2R_MESAU | Neurokinin 2 receptor | Neurokinin NK2 | TAC2R | TACR2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43436.75 |
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| Organism: | HAMSTER |
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| Description: | P51144 |
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| Residue: | 384 |
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| Sequence: | MGGRAIVTDTNIFSGLESNTTGVTAFSMPAWQLALWATAYLGLVLVAVTGNATVIWIILA
HERMRTVTNYFIINLALADLCMAAFNATFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
IYSMTAIAADRYMAIVHPFQPRLSAPITKATIAGIWLVALALASPQCFYSTITVDQGATK
CVVAWPNDNGGKMLLLYHLVVFVLVYFLPLVVMFVAYSVIGLTLWKRAVPRHQAHGANLR
HLHAKKKFVKAMVLVVLTFAICWLPYHLYFILGSFQKDIYYRKFIQQVYLALFWLAMSST
MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDRLELTRTPSLSRRVNRCHTKETLFMT
ADMTHSEATNGQVGSPQDVEPAAP
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| BDBM82262 |
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| n/a |
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| Name | BDBM82262 |
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| Synonyms: | ZM253,270 |
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| Type | n/a |
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| Emp. Form. | C22H26ClN7O3 |
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| Mol. Mass. | 471.94 |
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| SMILES | CC(C)N1Cc2c(nc(nc2Nc2ccc(Cl)cc2)N2CCN(CC2)C(=O)C(C)N=O)C1=O |
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| Structure | 
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