Compile Data Set for Download or QSAR

Found 122 hits with Last Name = 'buckner' and Initial = 'ck'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469804 (CHEMBL339277) Show SMILES CCCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC1CCCC1 Show InChI InChI=1S/C34H39N3O5S/c1-4-17-37-22-28(29-19-26(15-16-30(29)37)33(38)35-21-24-10-6-7-11-24)18-25-13-14-27(20-31(25)42-3)34(39)36-43(40,41)32-12-8-5-9-23(32)2/h5,8-9,12-16,19-20,22,24H,4,6-7,10-11,17-18,21H2,1-3H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50009073 (4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041356 (1-Ethyl-3-[2-methoxy-4-(toluene-2-sulfonylaminocar...) Show SMILES CCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(C)CC(F)(F)F Show InChI InChI=1S/C32H34F3N3O5S/c1-5-38-19-25(26-15-23(12-13-27(26)38)30(39)36-18-20(2)17-32(33,34)35)14-22-10-11-24(16-28(22)43-4)31(40)37-44(41,42)29-9-7-6-8-21(29)3/h6-13,15-16,19-20H,5,14,17-18H2,1-4H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469821 (CHEMBL130463) Show SMILES COc1cc(ccc1Cc1cn(CC=C)c2ccc(cc12)C(=O)NCC1CCCC1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C34H37N3O5S/c1-4-17-37-22-28(29-19-26(15-16-30(29)37)33(38)35-21-24-10-6-7-11-24)18-25-13-14-27(20-31(25)42-3)34(39)36-43(40,41)32-12-8-5-9-23(32)2/h4-5,8-9,12-16,19-20,22,24H,1,6-7,10-11,17-18,21H2,2-3H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041349 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NC[C@H](C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18-19H,13,16-17H2,1-4H3,(H,35,38)(H,36,39)/t19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041357 (1-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cn1cc(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(15-31(32,33)34)16-35-29(38)22-11-12-25-21(3)17-37(26(25)13-22)18-24-10-9-23(14-27(24)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-14,17,19H,15-16,18H2,1-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469816 (CHEMBL339242) Show SMILES CCC(CC)CNC(=O)c1ccc2n(cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C(C)C Show InChI InChI=1S/C34H41N3O5S/c1-7-24(8-2)20-35-33(38)26-15-16-30-29(18-26)28(21-37(30)22(3)4)17-25-13-14-27(19-31(25)42-6)34(39)36-43(40,41)32-12-10-9-11-23(32)5/h9-16,18-19,21-22,24H,7-8,17,20H2,1-6H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50000819 (2-Cyclopentyl-N-{3-[2-methoxy-4-(toluene-2-sulfony...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(NC(=O)CC3CCCC3)cc12)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H35N3O5S/c1-21-8-4-7-11-30(21)41(38,39)34-32(37)24-13-12-23(29(18-24)40-3)17-25-20-35(2)28-15-14-26(19-27(25)28)33-31(36)16-22-9-5-6-10-22/h4,7-8,11-15,18-20,22H,5-6,9-10,16-17H2,1-3H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041336 (3-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-met...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C30H29ClF3N3O5S/c1-18(15-30(32,33)34)16-35-28(38)20-10-11-25-23(13-20)22(17-37(25)2)12-19-8-9-21(14-26(19)42-3)29(39)36-43(40,41)27-7-5-4-6-24(27)31/h4-11,13-14,17-18H,12,15-16H2,1-3H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041344 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18-19H,13,16-17H2,1-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469811 (CHEMBL334122) Show SMILES CCCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(CC)CC Show InChI InChI=1S/C34H41N3O5S/c1-6-17-37-22-28(29-19-26(15-16-30(29)37)33(38)35-21-24(7-2)8-3)18-25-13-14-27(20-31(25)42-5)34(39)36-43(40,41)32-12-10-9-11-23(32)4/h9-16,19-20,22,24H,6-8,17-18,21H2,1-5H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50403654 (CHEMBL2115073) Show SMILES CCC(O)(CC)C1CCN(CC[C@H](CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 |r| Show InChI InChI=1S/C28H38Cl2N2O2/c1-4-28(34,5-2)24-14-17-32(18-15-24)16-13-23(22-11-12-25(29)26(30)19-22)20-31(3)27(33)21-9-7-6-8-10-21/h6-12,19,23-24,34H,4-5,13-18,20H2,1-3H3/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469809 (CHEMBL133790) Show SMILES CCC(CC)CNC(=O)c1ccc2c(CC3CCCC3)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C37H45N3O5S/c1-5-26(6-2)22-38-36(41)28-17-18-32-31(19-27-12-8-9-13-27)24-40(33(32)20-28)23-30-16-15-29(21-34(30)45-4)37(42)39-46(43,44)35-14-10-7-11-25(35)3/h7,10-11,14-18,20-21,24,26-27H,5-6,8-9,12-13,19,22-23H2,1-4H3,(H,38,41)(H,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469812 (CHEMBL131247) Show SMILES CCC(CC)CNC(=O)c1ccc2n(CC)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C33H39N3O5S/c1-6-23(7-2)20-34-32(37)25-15-16-29-28(18-25)27(21-36(29)8-3)17-24-13-14-26(19-30(24)41-5)33(38)35-42(39,40)31-12-10-9-11-22(31)4/h9-16,18-19,21,23H,6-8,17,20H2,1-5H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041350 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCCC(C(F)(F)F)C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H29F6N3O5S/c1-18-6-4-5-7-26(18)46(43,44)39-29(42)21-9-8-19(25(16-21)45-3)14-22-17-40(2)24-11-10-20(15-23(22)24)28(41)38-13-12-27(30(32,33)34)31(35,36)37/h4-11,15-17,27H,12-14H2,1-3H3,(H,38,41)(H,39,42)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071118 (CHEMBL2111522 | CHEMBL443264 | N-[2-(3,4-Dichloro-...) Show SMILES CCC(N=O)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C26H33Cl2N3O2/c1-3-25(29-33)19-11-14-31(15-12-19)16-13-22(21-9-10-23(27)24(28)17-21)18-30(2)26(32)20-7-5-4-6-8-20/h4-10,17,19,22,25H,3,11-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469819 (CHEMBL335889) Show SMILES CCC(CC)CNC(=O)c1ccc2n(Cc3ccccc3)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C38H41N3O5S/c1-5-27(6-2)23-39-37(42)30-18-19-34-33(21-30)32(25-41(34)24-28-13-8-7-9-14-28)20-29-16-17-31(22-35(29)46-4)38(43)40-47(44,45)36-15-11-10-12-26(36)3/h7-19,21-22,25,27H,5-6,20,23-24H2,1-4H3,(H,39,42)(H,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469801 (CHEMBL130872) Show SMILES CCCc1cn(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(CC)CC Show InChI InChI=1S/C34H41N3O5S/c1-6-11-27-21-37(30-18-25(16-17-29(27)30)33(38)35-20-24(7-2)8-3)22-28-15-14-26(19-31(28)42-5)34(39)36-43(40,41)32-13-10-9-12-23(32)4/h9-10,12-19,21,24H,6-8,11,20,22H2,1-5H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041352 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1CC(F)(F)C(F)(F)C1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H31F4N3O5S/c1-19-6-4-5-7-28(19)45(42,43)38-30(41)23-9-8-21(27(14-23)44-3)12-24-18-39(2)26-11-10-22(13-25(24)26)29(40)37-17-20-15-31(33,34)32(35,36)16-20/h4-11,13-14,18,20H,12,15-17H2,1-3H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041339 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NC[C@@H](C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H32F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18-19H,13,16-17H2,1-4H3,(H,35,38)(H,36,39)/t19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041353 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(C)CC(F)(F)F Show InChI InChI=1S/C33H36F3N3O5S/c1-5-14-39-20-26(27-16-24(12-13-28(27)39)31(40)37-19-21(2)18-33(34,35)36)15-23-10-11-25(17-29(23)44-4)32(41)38-45(42,43)30-9-7-6-8-22(30)3/h6-13,16-17,20-21H,5,14-15,18-19H2,1-4H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071112 (CHEMBL56835 | N-[4-(4-Acetylamino-4-phenyl-piperid...) Show SMILES CN(CC(CCN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C31H35Cl2N3O2/c1-23(37)34-31(27-11-7-4-8-12-27)16-19-36(20-17-31)18-15-26(25-13-14-28(32)29(33)21-25)22-35(2)30(38)24-9-5-3-6-10-24/h3-14,21,26H,15-20,22H2,1-2H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071112 (CHEMBL56835 | N-[4-(4-Acetylamino-4-phenyl-piperid...) Show SMILES CN(CC(CCN1CCC(CC1)(NC(C)=O)c1ccccc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C31H35Cl2N3O2/c1-23(37)34-31(27-11-7-4-8-12-27)16-19-36(20-17-31)18-15-26(25-13-14-28(32)29(33)21-25)22-35(2)30(38)24-9-5-3-6-10-24/h3-14,21,26H,15-20,22H2,1-2H3,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Substance-K receptor (HAMSTER)	BDBM82262 (ZM253,270) Show SMILES CC(C)N1Cc2c(nc(nc2Nc2ccc(Cl)cc2)N2CCN(CC2)C(=O)C(C)N=O)C1=O Show InChI InChI=1S/C22H26ClN7O3/c1-13(2)30-12-17-18(21(30)32)25-22(26-19(17)24-16-6-4-15(23)5-7-16)29-10-8-28(9-11-29)20(31)14(3)27-33/h4-7,13-14H,8-12H2,1-3H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by PDSP Ki Database									J Pharmacol Exp Ther 274: 1216-21 (1995) BindingDB Entry DOI: 10.7270/Q2VQ316V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469800 (CHEMBL130428) Show SMILES CCCn1cc(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2C)c2cc(ccc12)C(=O)NCC(C)C Show InChI InChI=1S/C32H37N3O5S/c1-6-15-35-20-26(27-17-24(13-14-28(27)35)31(36)33-19-21(2)3)16-23-11-12-25(18-29(23)40-5)32(37)34-41(38,39)30-10-8-7-9-22(30)4/h7-14,17-18,20-21H,6,15-16,19H2,1-5H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041341 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCC(CC)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C32H37N3O5S/c1-6-22(7-2)19-33-31(36)24-14-15-28-27(17-24)26(20-35(28)4)16-23-12-13-25(18-29(23)40-5)32(37)34-41(38,39)30-11-9-8-10-21(30)3/h8-15,17-18,20,22H,6-7,16,19H2,1-5H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041348 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NC\C(C)=C/C(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H30F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-16,18H,13,17H2,1-4H3,(H,35,38)(H,36,39)/b19-16-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50216091 (CHEMBL2111522) Show SMILES CC\C(=N\O)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C26H33Cl2N3O2/c1-3-25(29-33)19-11-14-31(15-12-19)16-13-22(21-9-10-23(27)24(28)17-21)18-30(2)26(32)20-7-5-4-6-8-20/h4-10,17,19,22,33H,3,11-16,18H2,1-2H3/b29-25-	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041360 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(C)(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H34F3N3O5S/c1-20-8-6-7-9-28(20)44(41,42)37-30(40)23-11-10-21(27(16-23)43-5)14-24-17-38(4)26-13-12-22(15-25(24)26)29(39)36-19-31(2,3)18-32(33,34)35/h6-13,15-17H,14,18-19H2,1-5H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Substance-K receptor (HAMSTER)	BDBM82262 (ZM253,270) Show SMILES CC(C)N1Cc2c(nc(nc2Nc2ccc(Cl)cc2)N2CCN(CC2)C(=O)C(C)N=O)C1=O Show InChI InChI=1S/C22H26ClN7O3/c1-13(2)30-12-17-18(21(30)32)25-22(26-19(17)24-16-6-4-15(23)5-7-16)29-10-8-28(9-11-29)20(31)14(3)27-33/h4-7,13-14H,8-12H2,1-3H3,(H,24,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by PDSP Ki Database									J Pharmacol Exp Ther 274: 1216-21 (1995) BindingDB Entry DOI: 10.7270/Q2VQ316V
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041337 (3-[4-(2-Bromo-benzenesulfonylaminocarbonyl)-2-meth...) Show SMILES CCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3Br)c2c1)CC(F)(F)F Show InChI InChI=1S/C31H31BrF3N3O5S/c1-4-19(16-31(33,34)35)17-36-29(39)21-11-12-26-24(14-21)23(18-38(26)2)13-20-9-10-22(15-27(20)43-3)30(40)37-44(41,42)28-8-6-5-7-25(28)32/h5-12,14-15,18-19H,4,13,16-17H2,1-3H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469826 (CHEMBL133788) Show SMILES CCC(CC)CNC(=O)c1ccc2c(CC3CCCCC3)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C38H47N3O5S/c1-5-27(6-2)23-39-37(42)29-18-19-33-32(20-28-13-8-7-9-14-28)25-41(34(33)21-29)24-31-17-16-30(22-35(31)46-4)38(43)40-47(44,45)36-15-11-10-12-26(36)3/h10-12,15-19,21-22,25,27-28H,5-9,13-14,20,23-24H2,1-4H3,(H,39,42)(H,40,43)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469824 (CHEMBL434053) Show SMILES CCC(CC)CNC(=O)c1ccc2c(C)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C32H37N3O5S/c1-6-23(7-2)18-33-31(36)24-14-15-27-22(4)19-35(28(27)16-24)20-26-13-12-25(17-29(26)40-5)32(37)34-41(38,39)30-11-9-8-10-21(30)3/h8-17,19,23H,6-7,18,20H2,1-5H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469797 (CHEMBL133398) Show SMILES CCC(CC)CNC(=O)c1ccc2n(cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C1CCCC1 Show InChI InChI=1S/C36H43N3O5S/c1-5-25(6-2)22-37-35(40)27-17-18-32-31(20-27)29(23-39(32)30-12-8-9-13-30)19-26-15-16-28(21-33(26)44-4)36(41)38-45(42,43)34-14-10-7-11-24(34)3/h7,10-11,14-18,20-21,23,25,30H,5-6,8-9,12-13,19,22H2,1-4H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071118 (CHEMBL2111522 | CHEMBL443264 | N-[2-(3,4-Dichloro-...) Show SMILES CCC(N=O)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C26H33Cl2N3O2/c1-3-25(29-33)19-11-14-31(15-12-19)16-13-22(21-9-10-23(27)24(28)17-21)18-30(2)26(32)20-7-5-4-6-8-20/h4-10,17,19,22,25H,3,11-16,18H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469789 (CHEMBL131148) Show SMILES CCC(CC)CNC(=O)c1ccc2c(CC)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C33H39N3O5S/c1-6-23(7-2)19-34-32(37)25-15-16-28-24(8-3)20-36(29(28)17-25)21-27-14-13-26(18-30(27)41-5)33(38)35-42(39,40)31-12-10-9-11-22(31)4/h9-18,20,23H,6-8,19,21H2,1-5H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50000817 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1CCCC1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H35N3O5S/c1-21-8-4-7-11-30(21)41(38,39)34-32(37)25-13-12-23(29(18-25)40-3)16-26-20-35(2)28-15-14-24(17-27(26)28)31(36)33-19-22-9-5-6-10-22/h4,7-8,11-15,17-18,20,22H,5-6,9-10,16,19H2,1-3H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50000817 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1CCCC1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H35N3O5S/c1-21-8-4-7-11-30(21)41(38,39)34-32(37)25-13-12-23(29(18-25)40-3)16-26-20-35(2)28-15-14-24(17-27(26)28)31(36)33-19-22-9-5-6-10-22/h4,7-8,11-15,17-18,20,22H,5-6,9-10,16,19H2,1-3H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071125 (CHEMBL56481 | N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-e...) Show SMILES CCC(O)(CC)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C28H38Cl2N2O2/c1-4-28(34,5-2)24-14-17-32(18-15-24)16-13-23(22-11-12-25(29)26(30)19-22)20-31(3)27(33)21-9-7-6-8-10-21/h6-12,19,23-24,34H,4-5,13-18,20H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071120 (CHEMBL56788 | N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...) Show SMILES CCCC(O)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C27H36Cl2N2O2/c1-3-7-26(32)20-12-15-31(16-13-20)17-14-23(22-10-11-24(28)25(29)18-22)19-30(2)27(33)21-8-5-4-6-9-21/h4-6,8-11,18,20,23,26,32H,3,7,12-17,19H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041345 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC(=C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C31H30F3N3O5S/c1-19(16-31(32,33)34)17-35-29(38)22-11-12-26-25(14-22)24(18-37(26)3)13-21-9-10-23(15-27(21)42-4)30(39)36-43(40,41)28-8-6-5-7-20(28)2/h5-12,14-15,18H,1,13,16-17H2,2-4H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469813 (CHEMBL337059) Show SMILES CCCc1cn(Cc2ccc(cc2OC)C(=O)NS(=O)(=O)c2ccccc2)c2cc(ccc12)C(=O)NCC(CC)CC Show InChI InChI=1S/C33H39N3O5S/c1-5-11-26-21-36(30-18-24(16-17-29(26)30)32(37)34-20-23(6-2)7-3)22-27-15-14-25(19-31(27)41-4)33(38)35-42(39,40)28-12-9-8-10-13-28/h8-10,12-19,21,23H,5-7,11,20,22H2,1-4H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50469815 (CHEMBL336101) Show SMILES CCC(CC)CNC(=O)c1ccc2c(C)cn(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3Br)c2c1 Show InChI InChI=1S/C31H34BrN3O5S/c1-5-21(6-2)17-33-30(36)22-13-14-25-20(3)18-35(27(25)15-22)19-24-12-11-23(16-28(24)40-4)31(37)34-41(38,39)29-10-8-7-9-26(29)32/h7-16,18,21H,5-6,17,19H2,1-4H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity against leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes using [3H]LTD4 as radio ligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041340 (1-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-met...) Show SMILES COc1cc(ccc1Cn1ccc2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C29H27ClF3N3O5S/c1-18(15-29(31,32)33)16-34-27(37)20-8-7-19-11-12-36(24(19)13-20)17-22-10-9-21(14-25(22)41-2)28(38)35-42(39,40)26-6-4-3-5-23(26)30/h3-14,18H,15-17H2,1-2H3,(H,34,37)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041347 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES COc1cc(ccc1Cc1cn(C)c2ccc(cc12)C(=O)NCC1(CC(F)(F)F)CC1)C(=O)NS(=O)(=O)c1ccccc1C Show InChI InChI=1S/C32H32F3N3O5S/c1-20-6-4-5-7-28(20)44(41,42)37-30(40)23-9-8-21(27(16-23)43-3)14-24-17-38(2)26-11-10-22(15-25(24)26)29(39)36-19-31(12-13-31)18-32(33,34)35/h4-11,15-17H,12-14,18-19H2,1-3H3,(H,36,39)(H,37,40)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041341 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCC(CC)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C32H37N3O5S/c1-6-22(7-2)19-33-31(36)24-14-15-28-27(17-24)26(20-35(28)4)16-23-12-13-25(18-29(23)40-5)32(37)34-41(38,39)30-11-9-8-10-21(30)3/h8-15,17-18,20,22H,6-7,16,19H2,1-5H3,(H,33,36)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Substance-K receptor (Homo sapiens (Human))	BDBM50071119 (CHEMBL56143 | N-{2-(3,4-Dichloro-phenyl)-4-[4-(1-h...) Show SMILES CCCC(O)(CCC)C1CCN(CCC(CN(C)C(=O)c2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 Show InChI InChI=1S/C30H42Cl2N2O2/c1-4-16-30(36,17-5-2)26-14-19-34(20-15-26)18-13-25(24-11-12-27(31)28(32)21-24)22-33(3)29(35)23-9-7-6-8-10-23/h6-12,21,25-26,36H,4-5,13-20,22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]- NKA from human NK-2 receptor expressed in MEL cells				Bioorg Med Chem Lett 8: 1935-40 (1999) BindingDB Entry DOI: 10.7270/Q2J38RPQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041355 (1-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-met...) Show SMILES COc1cc(ccc1Cn1cc(C)c2ccc(cc12)C(=O)NCC(C)CC(F)(F)F)C(=O)NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C30H29ClF3N3O5S/c1-18(14-30(32,33)34)15-35-28(38)20-10-11-23-19(2)16-37(25(23)12-20)17-22-9-8-21(13-26(22)42-3)29(39)36-43(40,41)27-7-5-4-6-24(27)31/h4-13,16,18H,14-15,17H2,1-3H3,(H,35,38)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041338 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCCCC(CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1)C(F)(F)F Show InChI InChI=1S/C33H36F3N3O5S/c1-5-6-10-26(33(34,35)36)19-37-31(40)23-14-15-28-27(17-23)25(20-39(28)3)16-22-12-13-24(18-29(22)44-4)32(41)38-45(42,43)30-11-8-7-9-21(30)2/h7-9,11-15,17-18,20,26H,5-6,10,16,19H2,1-4H3,(H,37,40)(H,38,41)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes				J Med Chem 37: 1282-97 (1994) BindingDB Entry DOI: 10.7270/Q2SN0812
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50041342 (3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...) Show SMILES CCC(C)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C31H35N3O5S/c1-6-20(2)18-32-30(35)23-13-14-27-26(16-23)25(19-34(27)4)15-22-11-12-24(17-28(22)39-5)31(36)33-40(37,38)29-10-8-7-9-21(29)3/h7-14,16-17,19-20H,6,15,18H2,1-5H3,(H,32,35)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Group Curated by ChEMBL					Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand				J Med Chem 36: 394-409 (1993) Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T
					More data for this Ligand-Target Pair

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