| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
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| Ligand | BDBM82273 |
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| Substrate/Competitor | n/a |
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| Ki | 0.79±n/a nM |
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| Comments | PDSP_1621 |
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| Citation |  Hegde, SS; Bonhaus, DW; Johnson, LG; Leung, E; Clark, RD; Eglen, RM RS 39604: a potent, selective and orally active 5-HT4 receptor antagonist. Br J Pharmacol115:1087-95 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 4 |
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| Name: | 5-hydroxytryptamine receptor 4 |
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| Synonyms: | 5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 43735.29 |
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| Organism: | GUINEA PIG |
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| Description: | 5-HT4 HTR4 GUINEA PIG::O70528 |
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| Residue: | 388 |
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| Sequence: | MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRP
QPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
TVECGGQWESQCHPAASSPLVAAQPIDT
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| BDBM82273 |
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| n/a |
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| Name | BDBM82273 |
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| Synonyms: | CAS_167710-87-4 | RS 39604 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H36ClN3O6S |
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| Mol. Mass. | 554.099 |
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| SMILES | COc1cc(COc2cc(N)c(Cl)cc2C(=O)CCC2CCN(CCNS(C)(=O)=O)CC2)cc(OC)c1 |
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| Structure | 
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