| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-lactamase |
|---|
| Ligand | BDBM83214 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) |
|---|
| IC50 | 4385±n/a nM |
|---|
| Citation |  PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-lactamase |
|---|
| Name: | Beta-lactamase |
|---|
| Synonyms: | Beta lactamase |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 31513.38 |
|---|
| Organism: | Pseudomonas aeruginosa |
|---|
| Description: | gi_114881106 |
|---|
| Residue: | 286 |
|---|
| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
|
|
|---|
| BDBM83214 |
|---|
| n/a |
|---|
| Name | BDBM83214 |
|---|
| Synonyms: | (2Z,6E)-4-methyl-2,6-bis[(1-methyl-2-pyrrolyl)methylidene]-1-cyclohexanone | (2Z,6E)-4-methyl-2,6-bis[(1-methylpyrrol-2-yl)methylene]cyclohexanone | (2Z,6E)-4-methyl-2,6-bis[(1-methylpyrrol-2-yl)methylidene]cyclohexan-1-one | MLS000519844 | SMR000130262 | cid_6371672 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H22N2O |
|---|
| Mol. Mass. | 294.3908 |
|---|
| SMILES | CC1C\C(=C\c2cccn2C)C(=O)\C(C1)=C\c1cccn1C |
|---|
| Structure | 
|
|---|
Search and Browse
