Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Beta-lactamase | ||
Ligand | BDBM51266 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) | ||
IC50 | 9371±n/a nM | ||
Citation | PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay(2011)[AID] | ||
More Info.: | Get all data from this article, Assay Method | ||
Beta-lactamase | |||
Name: | Beta-lactamase | ||
Synonyms: | Beta lactamase | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 31513.38 | ||
Organism: | Pseudomonas aeruginosa | ||
Description: | gi_114881106 | ||
Residue: | 286 | ||
Sequence: |
| ||
BDBM51266 | |||
n/a | |||
Name | BDBM51266 | ||
Synonyms: | 3-Benzoyl-5-(2-methoxy-phenyl)-1-phenyl-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione | 3-benzoyl-5-(2-methoxyphenyl)-1-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione | 3-benzoyl-5-(2-methoxyphenyl)-1-phenyl-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-quinone | 5-(2-methoxyphenyl)-1-phenyl-3-(phenylcarbonyl)-3a,6a-dihydropyrrolo[3,4-c]pyrazole-4,6-dione | MLS000769406 | SMR000434220 | cid_3565160 | ||
Type | Small organic molecule | ||
Emp. Form. | C25H19N3O4 | ||
Mol. Mass. | 425.4361 | ||
SMILES | COc1ccccc1-n1c(O)c2n([nH]c(C(=O)c3ccccc3)c2c1=O)-c1ccccc1 |(5.39,4.42,;6.16,3.08,;5.39,1.75,;3.85,1.75,;3.08,.41,;3.85,-.92,;5.39,-.92,;6.16,.41,;7.7,.41,;8.61,-.83,;8.13,-2.3,;10.07,-.36,;11.53,-.83,;12.43,.41,;11.53,1.65,;12.01,3.12,;10.98,4.26,;13.51,3.44,;13.99,4.9,;15.5,5.22,;16.53,4.07,;16.05,2.61,;14.54,2.29,;10.07,1.18,;8.61,1.66,;8.13,3.12,;12.01,-2.29,;13.51,-2.61,;13.99,-4.07,;12.96,-5.22,;11.46,-4.9,;10.98,-3.44,)| | ||
Structure |