| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM59520 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59703±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM59520 |
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| n/a |
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| Name | BDBM59520 |
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| Synonyms: | (E)-N-(3,5-dimethylphenyl)-3-(5-nitro-2-thienyl)acrylamide | (E)-N-(3,5-dimethylphenyl)-3-(5-nitro-2-thiophenyl)-2-propenamide | (E)-N-(3,5-dimethylphenyl)-3-(5-nitrothiophen-2-yl)prop-2-enamide | MLS000722301 | SMR000235997 | cid_6379206 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N2O3S |
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| Mol. Mass. | 302.348 |
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| SMILES | Cc1cc(C)cc(NC(=O)\C=C\c2ccc(s2)[N+]([O-])=O)c1 |
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| Structure | 
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