Reaction Details |
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Target | Orotidine 5'-phosphate decarboxylase |
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Ligand | BDBM42064 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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EC50 | >59641±n/a nM |
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Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Orotidine 5'-phosphate decarboxylase |
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Name: | Orotidine 5'-phosphate decarboxylase |
Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 30195.13 |
Organism: | Aspergillus niger |
Description: | gi_2395 |
Residue: | 277 |
Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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BDBM42064 |
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n/a |
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Name | BDBM42064 |
Synonyms: | 1-[1-(2-chlorophenyl)-2-keto-cyclohexyl]-3-cyclohexyl-1-methyl-thiourea | 1-[1-(2-chlorophenyl)-2-oxidanylidene-cyclohexyl]-3-cyclohexyl-1-methyl-thiourea | 1-[1-(2-chlorophenyl)-2-oxocyclohexyl]-3-cyclohexyl-1-methylthiourea | MLS000391056 | SMR000260093 | cid_4006073 |
Type | Small organic molecule |
Emp. Form. | C20H27ClN2OS |
Mol. Mass. | 378.959 |
SMILES | CN(C(=S)NC1CCCCC1)C1(CCCCC1=O)c1ccccc1Cl |
Structure |
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