| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM83825 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59585±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM83825 |
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| n/a |
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| Name | BDBM83825 |
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| Synonyms: | MLS002170809 | N-(1,3-benzodioxol-5-yl)-2-(4,5-dichloro-6-keto-pyridazin-1-yl)acetamide | N-(1,3-benzodioxol-5-yl)-2-(4,5-dichloro-6-oxo-1-pyridazinyl)acetamide | N-(1,3-benzodioxol-5-yl)-2-(4,5-dichloro-6-oxopyridazin-1-yl)acetamide | N-(1,3-benzodioxol-5-yl)-2-[4,5-bis(chloranyl)-6-oxidanylidene-pyridazin-1-yl]ethanamide | SMR001251119 | cid_2647474 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9Cl2N3O4 |
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| Mol. Mass. | 342.134 |
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| SMILES | Clc1cnn(CC(=O)Nc2ccc3OCOc3c2)c(=O)c1Cl |
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| Structure | 
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