| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM54853 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59631±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM54853 |
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| n/a |
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| Name | BDBM54853 |
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| Synonyms: | BRD-A94563302-001-04-8 | N-[4-[3-(3,6-dichloro-9-carbazolyl)-2-hydroxypropoxy]phenyl]-N-methylacetamide | N-[4-[3-(3,6-dichlorocarbazol-9-yl)-2-hydroxy-propoxy]phenyl]-N-methyl-acetamide | N-[4-[3-(3,6-dichlorocarbazol-9-yl)-2-hydroxypropoxy]phenyl]-N-methylacetamide | N-[4-[3-[3,6-bis(chloranyl)carbazol-9-yl]-2-oxidanyl-propoxy]phenyl]-N-methyl-ethanamide | cid_2920939 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22Cl2N2O3 |
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| Mol. Mass. | 457.349 |
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| SMILES | CN(C(C)=O)c1ccc(OCC(O)Cn2c3ccc(Cl)cc3c3cc(Cl)ccc23)cc1 |
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| Structure | 
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