| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM71687 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59623±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM71687 |
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| n/a |
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| Name | BDBM71687 |
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| Synonyms: | 4-(1-benzotriazolyl)-5-(8-quinolinyloxy)benzene-1,2-dicarbonitrile | 4-(benzotriazol-1-yl)-5-(8-quinolyloxy)phthalonitrile | 4-(benzotriazol-1-yl)-5-quinolin-8-yloxy-benzene-1,2-dicarbonitrile | 4-(benzotriazol-1-yl)-5-quinolin-8-yloxybenzene-1,2-dicarbonitrile | MLS000037251 | SMR000036468 | cid_662882 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H12N6O |
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| Mol. Mass. | 388.381 |
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| SMILES | N#Cc1cc(Oc2cccc3cccnc23)c(cc1C#N)-n1nnc2ccccc12 |
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| Structure | 
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