| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM83862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59647±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM83862 |
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| n/a |
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| Name | BDBM83862 |
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| Synonyms: | 2-[[2-keto-2-[2-morpholino-5-(trifluoromethyl)anilino]ethyl]thio]-N-(m-tolyl)acetamide | MLS001099392 | N-(3-methylphenyl)-2-[2-[2-morpholin-4-yl-5-(trifluoromethyl)anilino]-2-oxoethyl]sulfanylacetamide | N-(3-methylphenyl)-2-[2-[[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]amino]-2-oxidanylidene-ethyl]sulfanyl-ethanamide | N-(3-methylphenyl)-2-[[2-[2-(4-morpholinyl)-5-(trifluoromethyl)anilino]-2-oxoethyl]thio]acetamide | SMR000717748 | cid_24687588 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24F3N3O3S |
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| Mol. Mass. | 467.504 |
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| SMILES | Cc1cccc(NC(=O)CSCC(=O)Nc2cc(ccc2N2CCOCC2)C(F)(F)F)c1 |
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| Structure | 
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