| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM83863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59613±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM83863 |
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| n/a |
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| Name | BDBM83863 |
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| Synonyms: | MLS003122004 | N-cyclohexyl-2-keto-3-[2-methoxy-5-(trifluoromethoxy)benzyl]-3-methyl-indoline-5-sulfonamide | N-cyclohexyl-3-[[2-methoxy-5-(trifluoromethoxy)phenyl]methyl]-3-methyl-2-oxo-1H-indole-5-sulfonamide | N-cyclohexyl-3-[[2-methoxy-5-(trifluoromethyloxy)phenyl]methyl]-3-methyl-2-oxidanylidene-1H-indole-5-sulfonamide | SMR001819772 | cid_46948009 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27F3N2O5S |
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| Mol. Mass. | 512.542 |
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| SMILES | COc1ccc(OC(F)(F)F)cc1CC1(C)C(=O)Nc2ccc(cc12)S(=O)(=O)NC1CCCCC1 |
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| Structure | 
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