| Reaction Details |
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 | Report a problem with these data |
| Target | Orotidine 5'-phosphate decarboxylase |
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| Ligand | BDBM83866 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter |
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| EC50 | >59660±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for activators of the GAA850 frataxin (FXN) promoter PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Orotidine 5'-phosphate decarboxylase |
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| Name: | Orotidine 5'-phosphate decarboxylase |
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| Synonyms: | FXN frataxin | PYRF_ASPNG | pyrA | pyrG |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 30195.13 |
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| Organism: | Aspergillus niger |
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| Description: | gi_2395 |
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| Residue: | 277 |
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| Sequence: | MSSKSQLTYTARASKHPNALAKRLFEIAEAKKTNVTVSADVTTTKELLDLADRLGPYIAV
IKTHIDILSDFSDETIEGLKALAQKHNFLIFEDRKFIDIGNTVQKQYHRGTLRISEWAHI
INCSILPGEGIVEALAQTASAPDFSYGPERGLLILAEMTSKGSLATGQYTTSSVDYARKY
KNFVMGFVSTRSLGEVQSEVSSPSDEEDFVVFTTGVNISSKGDKLGQQYQTPASAIGRGA
DFIIAGRGIYAAPDPVQAAQQYQKEGWEAYLARVGGN
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| BDBM83866 |
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| n/a |
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| Name | BDBM83866 |
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| Synonyms: | 1-[4-[1-amino-2-(4-methoxyphenyl)ethyl]-1,3-thiazol-2-yl]-3-(2-benzylphenyl)urea | 1-[4-[1-amino-2-(4-methoxyphenyl)ethyl]-2-thiazolyl]-3-[2-(phenylmethyl)phenyl]urea | 1-[4-[1-amino-2-(4-methoxyphenyl)ethyl]thiazol-2-yl]-3-(2-benzylphenyl)urea | 1-[4-[1-azanyl-2-(4-methoxyphenyl)ethyl]-1,3-thiazol-2-yl]-3-[2-(phenylmethyl)phenyl]urea | MLS003123997 | SMR001292272 | cid_49786793 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H26N4O2S |
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| Mol. Mass. | 458.575 |
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| SMILES | COc1ccc(CC(N)c2csc(NC(=O)Nc3ccccc3Cc3ccccc3)n2)cc1 |
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| Structure | 
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