| Reaction Details |
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 | Report a problem with these data |
| Target | dCTP pyrophosphatase 1 |
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| Ligand | BDBM50260220 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1693435 |
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| IC50 | 1400±n/a nM |
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| Citation |  Llona-Minguez, S; Häggblad, M; Martens, U; Johansson, L; Sigmundsson, K; Lundbäck, T; Loseva, O; Jemth, AS; Lundgren, B; Jensen, AJ; Scobie, M; Helleday, T Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems. Bioorg Med Chem Lett27:3219-3225 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| dCTP pyrophosphatase 1 |
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| Name: | dCTP pyrophosphatase 1 |
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| Synonyms: | DCTP1_HUMAN | DCTPP1 | Deoxycytidine-triphosphatase 1 | XTP3TPA | dCTP pyrophosphatase 1 | dCTP pyrophosphatase 1 (DCTPP1) |
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| Type: | Protein |
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| Mol. Mass.: | 18673.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H773 |
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| Residue: | 170 |
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| Sequence: | MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLAL
VGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLS
KMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST
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| BDBM50260220 |
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| n/a |
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| Name | BDBM50260220 |
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| Synonyms: | CHEMBL4099630 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H17N3O2S |
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| Mol. Mass. | 327.401 |
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| SMILES | CC(NC(=O)c1cnc2sc(C)c(C)n2c1=O)c1ccccc1 |
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| Structure | 
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