Reaction Details |
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Target | Psychosine receptor |
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Ligand | BDBM50260350 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_1693533 |
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IC50 | >30000±n/a nM |
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Citation | Miltz, W; Velcicky, J; Dawson, J; Littlewood-Evans, A; Ludwig, MG; Seuwen, K; Feifel, R; Oberhauser, B; Meyer, A; Gabriel, D; Nash, M; Loetscher, P Design and synthesis of potent and orally active GPR4 antagonists with modulatory effects on nociception, inflammation, and angiogenesis. Bioorg Med Chem25:4512-4525 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Psychosine receptor |
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Name: | Psychosine receptor |
Synonyms: | G-protein coupled receptor 65 | GPR65 | PSYR_HUMAN | Psychosine receptor | T-cell death-associated gene 8 protein | TDAG8 |
Type: | PROTEIN |
Mol. Mass.: | 39338.77 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_116042 |
Residue: | 337 |
Sequence: | MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSD
LLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPL
KFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQ
INLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFT
PFHVMLLIRCILEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYD
MWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE
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BDBM50260350 |
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n/a |
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Name | BDBM50260350 |
Synonyms: | CHEMBL4078089 |
Type | Small organic molecule |
Emp. Form. | C27H36N6 |
Mol. Mass. | 444.6149 |
SMILES | CC(C)N1CCN(CC#Cc2ccc(CN(CC(C)(C)C)c3ccnc(n3)C#N)cc2)CC1 |
Structure |
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