| Reaction Details |
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 | Report a problem with these data |
| Target | Signal transducer and activator of transcription 5B |
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| Ligand | BDBM50267862 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1704106 (CHEMBL4055339) |
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| IC50 | 460±n/a nM |
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| Citation |  Elumalai, N; Natarajan, K; Berg, T Halogen-substituted catechol bisphosphates are potent and selective inhibitors of the transcription factor STAT5b. Bioorg Med Chem25:3871-3882 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Signal transducer and activator of transcription 5B |
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| Name: | Signal transducer and activator of transcription 5B |
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| Synonyms: | STA5B_HUMAN | STAT5B | Signal transducer and activator of transcription 5B | Transcription factor STAT5b (STAT5b) |
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| Type: | Protein |
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| Mol. Mass.: | 89858.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 787 |
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| Sequence: | MAVWIQAQQLQGEALHQMQALYGQHFPIEVRHYLSQWIESQAWDSVDLDNPQENIKATQL
LEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLV
REANNGSSPAGSLADAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESL
RIQAQFGPLAQLSPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLL
RKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLC
QQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKL
NVHMNPPQVKATIISEQQAKSLLKNENTRNDYSGEILNNCCVMEYHQATGTLSAHFRNMS
LKRIKRSDRRGAESVTEEKFTILFESQFSVGGNELVFQVKTLSLPVVVIVHGSQDNNATA
TVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNN
SSSHLEDYSGLSVSWSQFNRENLPGRNYTFWQWFDGVMEVLKKHLKPHWNDGAILGFVNK
QQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSQERMFWNLMPFTTRDFSIRSLADRL
GDLNYLIYVFPDRPKDEVYSKYYTPVPCESATAKAVDGYVKPQIKQVVPEFVNASADAGG
GSATYMDQAPSPAVCPQAHYNMYPQNPDSVLDTDGDFDLEDTMDVARRVEELLGRPMDSQ
WIPHAQS
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| BDBM50267862 |
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| n/a |
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| Name | BDBM50267862 |
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| Synonyms: | CHEMBL4075745 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21ClN2O11P2 |
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| Mol. Mass. | 586.809 |
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| SMILES | OP(O)(=O)Oc1ccc(CNC(=O)COc2ccc(cc2)C(=O)Nc2cccc(Cl)c2)cc1OP(O)(O)=O |
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| Structure | 
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