| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50274739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1714218 (CHEMBL4124267) |
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| IC50 | 0.901000±n/a nM |
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| Citation |  Willemse, T; Eiselt, E; Hollanders, K; Schepens, W; van Vlijmen, HWT; Chung, NN; Blais, V; Holleran, B; Longpré, JM; Schiller, PW; Maes, BUW; Sarret, P; Gendron, L; Ballet, S Chemical space screening around Phe Bioorg Med Chem Lett28:2320-2323 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 11165.58 |
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| Organism: | GUINEA PIG |
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| Description: | P97266 |
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| Residue: | 98 |
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| Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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|
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| BDBM50274739 |
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| n/a |
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| Name | BDBM50274739 |
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| Synonyms: | CHEMBL4127485 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H42N8O6 |
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| Mol. Mass. | 598.6938 |
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| SMILES | COc1ccc(C[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)C(=O)NCC(N)=O)cc1 |r| |
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| Structure | 
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