| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Estrogen receptor beta |
|---|
| Ligand | BDBM50276797 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1716406 |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Patch, RJ; Huang, H; Patel, S; Cheung, W; Xu, G; Zhao, BP; Beauchamp, DA; Rentzeperis, D; Geisler, JG; Askari, HB; Liu, J; Kasturi, J; Towers, M; Gaul, MD; Player, MR Indazole-based ligands for estrogen-related receptor ? as potential anti-diabetic agents. Eur J Med Chem138:830-853 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Estrogen receptor beta |
|---|
| Name: | Estrogen receptor beta |
|---|
| Synonyms: | ER-beta | ESR2 | ESR2_HUMAN | ESTRB | Estradiol receptor beta (ERβ) | Estrogen receptor | Estrogen receptor (ER beta) | Estrogen receptor beta | Estrogen receptor beta (ER beta) | Estrogen receptor beta (ER) | NR3A2 | Nuclear receptor subfamily 3 group A member 2 | estrogen beta |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 59238.43 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92731 |
|---|
| Residue: | 530 |
|---|
| Sequence: | MDIKNSPSSLNSPSSYNCSQSILPLEHGSIYIPSSYVDSHHEYPAMTFYSPAVMNYSIPS
NVTNLEGGPGRQTTSPNVLWPTPGHLSPLVVHRQLSHLYAEPQKSPWCEARSLEHTLPVN
RETLKRKVSGNRCASPVTGPGSKRDAHFCAVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRLVRRQRSADEQLH
CAGKAKRSGGHAPRVRELLLDALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTK
LADKELVHMISWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDA
DSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
CKNVVPVYDLLLEMLNAHVLRGCKSSITGSECSPAEDSKSKEGSQNPQSQ
|
|
|
|---|
| BDBM50276797 |
|---|
| n/a |
|---|
| Name | BDBM50276797 |
|---|
| Synonyms: | CHEMBL4174856 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H21ClF4N4O2S |
|---|
| Mol. Mass. | 552.971 |
|---|
| SMILES | CN1CC[C@H]([C@H](F)C1)N1C(=O)S\C(=C/c2ccc3n(Cc4ccc(Cl)cc4C(F)(F)F)ncc3c2)C1=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
