Ki Summary

Reaction Details

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Target

Cysteinyl leukotriene receptor 1

Ligand

BDBM50006816

Substrate/Competitor

n/a

Meas. Tech.

ChEBML_52357

2818±n/a nM

Citation

Matassa, VG; Maduskuie, TP; Shapiro, HS; Hesp, B; Snyder, DW; Aharony, D; Krell, RD; Keith, RA Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles. J Med Chem33:1781-90 (1990) [PubMed]

More Info.:

Get all data from this article, Assay Method

Cysteinyl leukotriene receptor 1

Name:

Cysteinyl leukotriene receptor 1

Synonyms:

CLTR1_CAVPO | CYSLTR1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

39007.58

Organism:

GUINEA PIG

Description:

Leukotriene D4 0 GUINEA PIG::Q2NNR5

Residue:

340

Sequence:

MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE

BDBM50006816

n/a

Name

BDBM50006816

Synonyms:

(LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone | 1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone | 1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone ( LY-171883) | 1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone(LY 171,883) | 1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone(LY-171883) | 1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone(LY171883) | 1-{2-Hydroxy-3-propyl-4-[4-(2H-tetrazol-5-yl)-butoxy]-phenyl}-ethanone | CHEMBL162358 | LY-171883

Type

Small organic molecule

Emp. Form.

C16H22N4O3

Mol. Mass.

318.3709

SMILES

CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O

Structure