| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase |
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| Ligand | BDBM50279660 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1721405 (CHEMBL4136405) |
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| Ki | 65±n/a nM |
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| Citation |  Nocentini, A; Cadoni, R; Del Prete, S; Capasso, C; Dumy, P; Gratteri, P; Supuran, CT; Winum, JY Benzoxaboroles as Efficient Inhibitors of the ?-Carbonic Anhydrases from Pathogenic Fungi: Activity and Modeling Study. ACS Med Chem Lett8:1194-1198 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase |
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| Name: | Carbonic anhydrase |
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| Synonyms: | Carbonic Anhydrase 2 (Can2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 26594.37 |
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| Organism: | Cryptococcus neoformans var. grubii (Filobasidiella neoformans var. grubii) |
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| Description: | n/a |
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| Residue: | 239 |
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| Sequence: | MPFHAEPLKPSDEIDMDLGHSVAAQKFKEIREVLEGNRYWARKVTSEEPEFMAEQVKGQA
PNFLWIGCADSRVPEVTIMARKPGDVFVQRNVANQFKPEDDSSQALLNYAIMNVGVTHVM
VVGHTGCGGCIAAFDQPLPTEENPGGTPLVRYLEPIIRLKHSLPEGSDVNDLIKENVKMA
VKNVVNSPTIQGAWEQARKGEFREVFVHGWLYDLSTGNIVDLNVTQGPHPFVDDRVPRA
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| BDBM50279660 |
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| n/a |
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| Name | BDBM50279660 |
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| Synonyms: | CHEMBL4171057 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15BN2O4 |
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| Mol. Mass. | 310.112 |
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| SMILES | CC(=O)c1ccc(NC(=O)Nc2ccc3COB(O)c3c2)cc1 |
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| Structure | 
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